Current global situation of Chagas disease.

Current situation of Chagas disease in Central America.

Chagas disease in Central America is known since 1913 when the first human case was reported in El Salvador. The other Central American countries reported their first cases between 1933 and 1967. On October 1997 was launched the Central American Initiative for Chagas Disease Control (IPCA). The objectives of this sub-regional Initiative are: (1) the elimination of Rhodnius prolixus in Central A...

Burden of Disease: Current Situation and Trends

Chagas disease: moving towards global elimination.

The WHO Global Network for Chagas Elimination was launched in July, 2007, to coordinate global eff orts to eliminate this neglected disease in the next 3 years. Jean Jannin, coordinator of the initiative at WHO’s neglected tropical diseases unit (Geneva, Switzerland) told TLID that the target date of 2010 is “perhaps optimistic” but he hopes the project will substantially reduce the global burd...

Chagas Disease Has Now Gone Global

1 Department of Pathology (Division of Parasitology), Albert Einstein College of Medicine, Bronx, New York, United States of America, 2 Department of Medicine (Division of Infectious Disease), Albert Einstein College of Medicine, Bronx, New York, United States of America, 3 Global Health Center, Albert Einstein College of Medicine, Bronx, New York, United States of America, 4 Jacobi Medical Cen...

Chagas disease cardiomyopathy: current concepts of an old disease.

Chagas disease continues to be a significant public health problem, as ca. 10 million people are still infected with T. cruzi in Latin America. Decades after primary infection, 30% of individuals can develop a form of chronic inflammatory cardiomyopathy known as Chagas disease cardiomyopathy (CCC). Data from both murine models and human studies support the view that an autoimmune response as we...